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400-6111-883
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400-6111-883
Recombinant Human MMP-14
产品货号:92548ES10
产品规格:10 μg
产品价格:¥ 1855.00
类别:细胞因子

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  • Product Information

     

    Product Name

    Cat#

    Size

    Price¥

    Recombinant Human Matrix metalloproteinase-14 (Human MMP-14)

    92548ES10

    10 μg

    1855.00

    92548ES60

    100 μg

    13615.00

    92548ES76

    500 μg

    35395.00

     

    Product Description

     

    As the first member of membrane type (MT) MMPs, MMP-14, also known as MT1-MMP, plays an important role in extracellular matrix (ECM) remodeling by being able to degrade type I collagen, activate pro-MMP-2 and process cell adhesion molecules such as CD44 and integrin alpha V. MMP-14 is therefore a key enzyme in many physiological and pathological processes such as angiogenesis and tumor invasion. Structurally, MMP-14 consists of the following domains: a pro domain containing the furin cleavage site, a catalytic domain containing the zinc-binding site, a hinge region, a hemopexin-like domain, a transmembrane domain, and a cytoplamasic tail.

     

    Product Properties

     

    Synonyms

    MMP-X1, MT-MMP 1, MT1-MMP

    Accession

    GeneID

    Source

    E.coli-derived human MMP-14 protein, Ala21-Gly284.

    Molecular Weight

    Approximately 29.6 kDa.

    AA Sequence

    ALASLGSAQS SSFSPEAWLQ QYGYLPPGDL RTHTQRSPQS LSAAIAAMQK FYGLQVTGKA DADTMKAMRR PRCGVPDKFG AEIKANVRRK RYAIQGLKWQ HNEITFCIQN YTPKVGEYAT YEAIRKAFRV WESATPLRFR EVPYAYIREG HEKQADIMIF FAEGFHGDST PFDGEGGFLA HAYFPGPNIG GDTHFDSAEP WTVRNEDLNG NDIFLVAVHE LGHALGLEHS SDPSAIMAPF YQWMDTENFV LPDDDRRGIQ QLYG

    Tag

    None

    Physical Appearance

    Sterile colorless liquid.

    Purity

    >95% by SDS-PAGE and HPLC analyses.

    Biological Activity

    Test in Process.

    Endotoxin

    < 1.0 EU per 1μg of the protein by the LAL method.

    Formulation

    Lyophilized from a 0.2 μm filtered concentrated solution in 20 mM Tris-HCl, pH 7.4, 300 mM NaCl, 3 mM CaCl2, 10 μM ZnCl2, with 30% glycerol.

     

    Shipping and Storage

     

    The products are shipped with ice pack and can be stored at -20℃ to -80 for 6 moths.

    Recommend to aliquot the protein into smaller quantities when first used and avoid repeated freeze-thaw cycles.

     


    Cautions

     

    1. Avoid repeated freeze-thaw cycles.

    2. For your safety and health, please wear lab coats and disposable gloves for operation.

    3.For research use only!

     

    HB220429