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400-6111-883
Recombinant Human Proinsulin C-Peptide Analogue
产品货号:92507ES10
产品规格:10 μg
产品价格:¥ 815.00
类别:细胞因子

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  • Product Information

     

    Product Name

    Cat#

    Size

    Price¥

    Recombinant Human Proinsulin C-Peptide Analogue

    (Human Proinsulin C-Peptide Analogue)

    92507ES10

    10 μg

    815.00

    92507ES60

    100 μg

    3125.00

    92507ES76

    500 μg

    7965.00

     

    Product Description

     

    This gene encodes insulin, a peptide hormone that plays a vital role in the regulation of carbohydrate and lipid metabolism. After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. Alternative splicing results in multiple transcript variants.

     

    Product Properties

     

    Synonyms

    Human Proinsulin C-Peptide Analogue, IDDM Protein, Human; IDDM1 Protein, Human

    Accession

    GeneID

    3630

    Source

    E.coli-derived human Proinsulin C-Peptide Analogue protein,Arg55-Arg89

    Molecular Weight

    Approximately 3.6 kDa.

    AA Sequence

    RREAEDLQVG QVELGGGPGA GSLQPLALEG SLQKR

    Tag

    None

    Physical Appearance

    Sterile Filtered White lyophilized (freeze-dried) powder.

    Purity

    > 95 % by SDS-PAGE and HPLC analyses.

    Biological Activity

    Data Not Available.

    Endotoxin

    0.1 EU per 1μg of the protein by the LAL method.

    Formulation

    Lyophilized from a 0.2 µm filtered solution in PBS, pH 7.4.

    Reconstitution

    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20°C. Further dilutions should be made in appropriate buffered solutions.

     

    Shipping and Storage

     

    The products are shipped with ice pack and can be stored at -20℃ to -80℃ for 1 year.

    Recommend to aliquot the protein into smaller quantities when first used and avoid repeated freeze-thaw cycles.

     

    Cautions

     

    1. Avoid repeated freeze-thaw cycles.

    2. For your safety and health, please wear lab coats and disposable gloves for operation.

    3. For research use only!


    HB220210