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400-6111-883
Recombinant Rat Neutrophil Activating Peptide 2/CXCL7 (Rat NAP-2/CXCL7)
产品货号:90939ES10
产品规格:10 μg
产品价格:¥ 1855.00
类别:细胞因子

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  • Product Information

     

    Product Name

    Cat#

    Size

    Price(¥

    Recombinant Rat Neutrophil Activating Peptide 2/CXCL7

    (Rat NAP-2/CXCL7)

    90939ES10

    10 μg

    1855.00

    90939ES60

    100 μg

    7865.00

    90939ES76

    500 μg

    20425.00

     

    Product Description

     

    CXCL7 is a small cytokine which is also an isoform of Beta-Thromboglobulin or Pro-Platelet basic protein belonging to the CXC chemokine family and it is released in large amounts from platelets following their activation. The rat CXCL7 shares 58 % and 77 % a.a. sequence identity with human and mouse CXCL7. CXCL7 stimulates DNA synthesis, mitosis, glycolysis, intracellular cAMP accumulation, prostaglandin E2 secretion, and synthesis of hyaluronic acid and sulfated glycosaminoglycan. It also stimulates the formation and secretion of plasminogen activator by human synovial cells. 

     

    Product Properties

     

    Synonyms

    CXC Chemokine RTCK1, Chemokine (C-X-C Motif) Ligand 7, Isoform CRA_b, Thymus Chemokine-1, Protein Ppbp

    Accession

    UniGene

    Rn.67082

    Source

    E.coli-derived rat NAP-2/CXCL7 protein, Ile46-Ile107.

    Molecular Weight

    Approximately 6.8 kDa.

    AA Sequence

    IELRCRCTNT LSGIPLNSIS RVNVFRPGAH CDNVEVIATL KNGKEVCLDP TAPMIKKIVK KI

    Tag

    None

    Physical Appearance

    Sterile Filtered White lyophilized (freeze-dried) powder.

    Purity

    >97% by SDS-PAGE and HPLC analyses.

    Biological Activity

    The biologically active determined by a chemotaxis bioassay using human CXCR2 transfected mouse BaF3 cells is in a concentration range of 0.1-1.0 ng/mL. Fully biologically active when compared to standard.

    Endotoxin

    < 1.0 EU per 1μg of the protein by the LAL method.

    Formulation

    Lyophilized from a 0.2 μm filtered concentrated solution in PBS, pH 7.4.

    Reconstitution

    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20. Further dilutions should be made in appropriate buffered solutions.

     

    Shipping and Storage

     

    The products are shipped with ice pack and can be stored at -20 to -80 for 1 year.

    Recommend to aliquot the protein into smaller quantities when first used and avoid repeated freeze-thaw cycles.

     

    Cautions


    1. Avoid repeated freeze-thaw cycles.

    2. For your safety and health, please wear lab coats and disposable gloves for operation.

    3. For research use only!

     

    HB220411