上海 外菜 vx

您好,欢迎来到YEASEN!
400-6111-883
| |
400-6111-883
Recombinant Rat LPS-induced CXC Chemokine/CXCL5 (Rat LIX/CXCL5)
产品货号:90938ES08
产品规格:5 μg
产品价格:¥ 815.00
类别:细胞因子

说明书下载

  • Product Information

     

    Product Name

    Cat#

    Size

    Price(¥

    Recombinant Rat LPS-induced CXC Chemokine/CXCL5

    (Rat LIX/CXCL5)

    90938ES08

    5 μg

    815.00

    90938ES60

    100 μg

    7865.00

    90938ES76

    500 μg

    20425.00

     

    Product Description

     

    CXCL5 (epithelial neutrophil-activating peptide-78) is a member of a proangiogenic subgroup of the CXC-type chemokine family of small, secreted proteins. Human CXCL5 shares 57% amino acid (aa) sequence identity with mouse and rat CXCL5. Full length CXCL5 (78 aa) is trimmed at the N-terminus by cathepsin G and chymotrypsin to ENA-74 (74 aa) and ENA-70 (70 aa), with the shortened forms showing increased potency relative to full length CXCL5. CXCL5 which acts as a potent chemoattractant and activator of neutrophil function was reported to play a multifaceted role in tumorigenesis. CXCL5 targeted therapy would prevent not only the development of type II diabetes in obese subjects, but also several other obesity-related co morbidities.

     

    Product Properties

     

    Synonyms

    chemokine (C-C motif) ligand 5, C-X-C motif chemokine 5, CXCL5, CXCL5/ENA-78, Cytokine LIX, ENA-78, Neutrophil-activating peptide ENA-78, neutrophil-activating protein 78, SCYB5ENA78, Small-inducible Cytokine B5

    Accession

    GeneID

    Source

    E.coli-derived rat LIX/CXCL5 protein, Ala38-Gln130.

    Molecular Weight

    Approximately 10.1 kDa.

    AA Sequence

    APFSAMVATE LRCVCLTLAP RINPKMIANL EVIPAGPHCP KVEVIAKLKN QKDNVCLDPQ APLIKKVIQK ILGSENKKTK RNALALVRSA STQ

    Tag

    None

    Physical Appearance

    Sterile Filtered White lyophilized (freeze-dried) powder.

    Purity

    >97% by SDS-PAGE and HPLC analyses.

    Biological Activity

    The biological activity determined by a chemotaxis bioassay using human peripheral blood neutrophils is in a concentration of 10-100 ng/ml. Fully biologically active when compared to standard.

    Endotoxin

    < 1.0 EU per 1μg of the protein by the LAL method.

    Formulation

    Lyophilized from a 0.2 μm filtered concentrated solution in 2 × PBS, pH 7.4.

    Reconstitution

    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20. Further dilutions should be made in appropriate buffered solutions.

     

    Shipping and Storage

     

    The products are shipped with ice pack and can be stored at -20 to -80 for 1 year.

    Recommend to aliquot the protein into smaller quantities when first used and avoid repeated freeze-thaw cycles.

     

    Cautions

     

    1. Avoid repeated freeze-thaw cycles.

    2. For your safety and health, please wear lab coats and disposable gloves for operation.

    3. For research use only!

     

    HB220401