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400-6111-883
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400-6111-883
Recombinant Mouse Stromal-Cell Derived Factor-1 alpha/CXCL12α (Mouse SDF-1α/CXCL12α)
产品货号:90929ES10
产品规格:10 μg
产品价格:¥ 1855.00
类别:细胞因子

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  • Product Information

     

    Product Name

    Cat#

    Size

    Price(¥

    Recombinant Mouse Stromal-Cell Derived Factor-1 alpha/CXCL12α (Mouse SDF-1α/CXCL12α)

    90929ES10

    10 μg

    1855.00

    90929ES60

    100 μg

    7865.00

    90929ES76

    500 μg

    20425.00

     

    Product Description

     

    CXCL12 also known as SDF-1 is belonging to the CXC chemokine family. SDF1 alpha  and SDF1 beta cDNAs encode precursor proteins of 89 and 93 amino acid residues, respectively. Both SDF-1 alpha and SDF1 beta are encoded by a single gene and arise by alternative splicing. SDF-1 is highly conserved between species, mouse CXCL12α shares approximately 93% amino acid sequence identity with human CXCL12α. CXCL12 is strongly chemotactic for T-lymphocytes, monocytes, but not neutrophils. Contrast to SDF-1β, SDF-1α is shorter by four amino acids at the C-terminal tail. And the CXCL12 plays an important pathogenic role in pulmonary hypertension.

     

    Product Properties

     

    Synonyms

    CXCL12 chemokine (C-X-C motif) ligand 12, CXCL12/SDF-1 alpha, IRH, PBSF, SCYB12, SDF1 alpha,  SDF1, SDF1a, SDF1B, TLSF, TPAR1

    Accession

    GeneID

    Source

    E.coli-derived mouse SDF-1α/CXCL12α protein, Lys22-Lys89.

    Molecular Weight

    Approximately 8.0 kDa.

    AA Sequence

    KPVSLSYRCP CRFFESHIAR ANVKHLKILN TPNCALQIVA RLKNNNRQVC IDPKLKWIQE YLEKALNK

    Tag

    None

    Physical Appearance

    Sterile Filtered White lyophilized (freeze-dried) powder.

    Purity

    >97% by SDS-PAGE and HPLC analyses.

    Biological Activity

    The biological activity determined by a chemotaxis bioassay using human peripheral blood monocytes is in a concentration range of 50-100 ng/mL. Fully biologically active when compared to standard.

    Endotoxin

    < 1.0 EU per 1μg of the protein by the LAL method.

    Formulation

    Lyophilized from a 0.2 μm filtered concentrated solution in PBS, pH 7.4.

    Reconstitution

    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20℃. Further dilutions should be made in appropriate buffered solutions.

     

    Shipping and Storage

     

    The products are shipped with ice pack and can be stored at -20 to -80 for 1 year.

    Recommend to aliquot the protein into smaller quantities when first used and avoid repeated freeze-thaw cycles.

     

    Cautions


    1. Avoid repeated freeze-thaw cycles.

    2. For your safety and health, please wear lab coats and disposable gloves for operation.

    3. For research use only!

     

    HB220407