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400-6111-883
Recombinant Mouse gamma-Interferon Inducible Protein 10/CXCL10 (Mouse IP-10/CXCL10)
产品货号:90927ES08
产品规格:5 μg
产品价格:¥ 815.00
类别:细胞因子

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  • Product Information

     

    Product Name

    Cat#

    Size

    Price(¥

    Recombinant Mouse gamma-Interferon Inducible Protein 10/CXCL10 (Mouse IP-10/CXCL10)

    90927ES08

    5 μg

    815.00

    90927ES60

    100 μg

    7865.00

    90927ES76

    500 μg

    20425.00

     

    Product Description

     

    C-X-C motif chemokine 10 (CXCL10) also known as interferon γ-induced protein 10kDa (IP-10) or small-inducible cytokine B10 is a cytokine belonging to the CXC chemokine family. And in murine it is also named the CRG-2 gene. Mouse CXCL10 shares approximately 67% amino acid sequence identity with human CXCL10. CXCL10 has been shown to be a chemoattractant for activated T-lymphocytes and monocytes. It also has other roles, such aspromotion of T cell adhesion to endothelial cells,  and inhibition of bone marrow colony formation and angiogenesis. CXCL10 binds CXCR3 receptor to induce chemotaxis, apoptosis, cell growth and angiostasis. CXCL10 play an important role in the initial phases of autoimmune thyroid disorders.

     

    Product Properties

     

    Synonyms

    Gamma-IP10, Small-inducible Cytokine B10, C7, CXCL10, gIP-10, IFI10, Interferon-gamma Induced Protein CRG-2

    Accession

    GeneID

    Source

    E.coli-derived mouse IP-10/CXCL10 protein, Ile22-Pro98.

    Molecular Weight

    Approximately 8.7 kDa.

    AA Sequence

    IPLARTVRCN CIHIDDGPVR MRAIGKLEII PASLSCPRVE IIATMKKNDE QRCLNPESKT IKNLMKAFSQ KRSKRAP

    Tag

    None

    Physical Appearance

    Sterile Filtered White lyophilized (freeze-dried) powder.

    Purity

    >97% by SDS-PAGE and HPLC analyses.

    Biological Activity

    The biologically active determined by a chemotaxis bioassay using human peripheral blood lymphocytes is in a concentration range of 0.1-10.0 ng/mL in the presence of IL-2. Fully biologically active when compared to standard.

    Endotoxin

    < 1.0 EU per 1μg of the protein by the LAL method.

    Formulation

    Lyophilized from a 0.2 μm filtered concentrated solution in 2 × PBS, pH 7.4.

    Reconstitution

    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/ml. Stock solutions should be apportioned into working aliquots and stored at ≤ -20℃. Further dilutions should be made in appropriate buffered solutions.

     

    Shipping and Storage

     

    The products are shipped with ice pack and can be stored at -20 to -80 for 1 year.

    Recommend to aliquot the protein into smaller quantities when first used and avoid repeated freeze-thaw cycles.


    Cautions

     

    1. Avoid repeated freeze-thaw cycles.

    2. For your safety and health, please wear lab coats and disposable gloves for operation.

    3. For research use only!

     

    HB220406