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400-6111-883
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400-6111-883
Recombinant Human Placenta Growth Factor-2 (Human PlGF-2)
产品货号:92519ES08
产品规格:5μg
产品价格:¥ 815.00
类别:细胞因子

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  • Product Information

     

    Product Name

    Cat#

    Size

    Price(¥

    Recombinant Human Placenta Growth Factor-2 (Human PlGF-2)

    92519ES08

    5μg

    815.00

    92519ES60

    100μg

    7865.00

    92519ES76

    500μg

    20425.00

     

    Product Description

     

    PlGF-2 is an angiogenic factor that belongs to the cysteine-knot superfamily of growth factors.  PlGF-2 is expressed in umbilical vein endothelial cells and placenta.  It signals through the VEGFR-1/FLT1 receptor, and stimulates endothelial cell proliferation and migration.  PlGF-2 also signals through Neuropilin (NP-1), and can bind with high affinity to heparin. Recombinant Human PlGF-2 is a 34.6 kDa disulfide-linked homodimeric protein of two 152 amino acid polypeptide chains.

     

    Product Properties

     

    Synonyms

    Placenta Growth Factor-2, PGFL

    Accession

    GeneID

    5228

    Source

    E.coli-derived Human PlGF-2 protein,Leu19-Arg131.

    Molecular Weight

    Approximately 34.6 kDa.

    AA Sequence

    LPAVPPQQWA LSAGNGSSEV EVVPFQEVWG RSYCRALERL VDVVSEYPSE VEHMFSPSCV SLLRCTGCCG DENLHCVPVE TANVTMQLLK IRSGDRPSYV ELTFSQHVRC ECRPLREKMK PERRRPKGRG KRRREKQRPT DCHLCGDAVP RR

    Tag

    None

    Physical Appearance

    Sterile Filtered White lyophilized (freeze-dried) powder.

    Purity

    > 97% by SDS-PAGE and HPLC analyses.

    Biological Activity

    Fully biologically active when compared to standard. The biologically active as determined by its ability to chemoattract human monocytes using a concentration range of 5.0-50 ng/mL.

    Endotoxin

    < 0.1 EU per 1μg of the protein by the LAL method.

    Formulation

    Lyophilized from a 0.2 μm filtered concentrated solution in PBS, pH 7.4, with 0.02 % Tween-20.

    Reconstitution

    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20°C. Further dilutions should be made in appropriate buffered solutions.

     

    Shipping and Storage

     

    The products are shipped with ice pack and can be stored at -20℃ to -80℃ for 1 year.

    Recommend to aliquot the protein into smaller quantities when first used and avoid repeated freeze-thaw cycles.

     

    Cautions

     

    1. Avoid repeated freeze-thaw cycles.

    2. For your safety and health, please wear lab coats and disposable gloves for operation.

    3. For research use only.

     

    HB220318