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Recombinant Human Fibroblast Growth Factor 17 (Human FGF-17)
产品货号：91310ES08
产品规格：5 μg
产品价格：¥ 815.00
类别：细胞因子

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  • Product Information

     

    Product Name

    Cat#

    Size

    Price（¥）

    Recombinant Human Fibroblast Growth Factor 17 (Human FGF-17)

    91310ES08

    5 μg

    815.00

    91310ES60

    100 μg

    7865.00

    91310ES76

    500 μg

    20425.00

     

    Product Description

     

    Fibroblast growth factor-17( FGF17) is one of the fibroblast growth factor( FGF) family members and it makes up FGF8 subfamily along with FGF8 and FGF18. Mature human FGF17 shares 99% aa identity with mouse, rat, porcine and canine FGF17. The FGF domain of FGF17 shares the most aa identity with FGF8 (~75%) and FGF18 (~64%). Among different members of the FGF family, FGF17 and FGF8 share high sequence homology and have similar patterns of expression during embryogenesis. FGF17 is also expressed in adult bovine ovarian follicles and the human prostate, and its expression is increased by both benign hypertrophy and cancer of the prostate.

     

    Product Properties

     

    Synonyms

    FGF17, FGF-17, fibroblast growth factor 17

    Accession

    GeneID

    Source

    E.coli-derived human FGF-17 protein, Thr23-Thr216, with an N-terminal Met.

    Molecular Weight

    Approximately 22.6 kDa.

    AA Sequence

    MTQGENHPSP NFNQYVRDQG AMTDQLSRRQ IREYQLYSRT SGKHVQVTGR RISATAEDGN KFAKLIVETD TFGSRVRIKG AESEKYICMN KRGKLIGKPS GKSKDCVFTE IVLENNYTAF QNARHEGWFM AFTRQGRPRQ ASRSRQNQRE AHFIKRLYQG QLPFPNHAEK QKQFEFVGSA PTRRTKRTRR PQPLT

    Tag

    None

    Physical Appearance

    Sterile Filtered White lyophilized (freeze-dried) powder.

    Purity

    >95% by SDS-PAGE and HPLC analyses.

    Biological Activity

    The ED50 as determined by a cell proliferation assay using murine balb/c 3T3 cells is less than 10 ng/ml, corresponding to a specific activity of >1.0 × 105 IU/mg. Fully biologically active when compared to standard.

    Endotoxin

    < 0.1 EU per 1μg of the protein by the LAL method.

    Formulation

    Lyophilized from a 0.2 μm filtered concentrated solution in PBS, pH 7.4.

    Reconstitution

    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/ml. Stock solutions should be apportioned into working aliquots and stored at ≤ -20℃. Further dilutions should be made in appropriate buffered solutions.

     

    Shipping and Storage

     

    The products are shipped with ice pack and can be stored at -20℃ to -80℃ for 1 year.

    Recommend to aliquot the protein into smaller quantities when first used and avoid repeated freeze-thaw cycles.

    Cautions

     

    Avoid repeated freeze-thaw cycles.

    For your safety and health, please wear lab coats and disposable gloves for operation.

    For research use only!

     

    HB220303